Clinical Characteristics of Concomitant Systemic Lupus Erythematosus and Primary Biliary Cirrhosis: A Literature Review

Primary autoimmune myelofibrosis: a report of three cases and review of the literature.

Myelofibrosis in association with autoimmune disorders has been consistently recognized in sporadic case reports over a number of years. Autoimmune myelofibrosis has been described most commonly in association with systemic lupus erythematosus (SLE). In addition, myelofibrosis presenting as cytopenias and showing clinical response to immunosuppressant drugs, notably steroids, has been reported ...

Unusual coexistence of systemic lupus erythematosus and primary biliary cirrhosis.

Systemic lupus erythematosus (SLE) and primary biliary cirrhosis (PBC) are distinct clinical disorders which rarely occur in the same patient. We report on a 65-year-old woman with coexistence of both conditions. Diagnosis of SLE was ascertained by the presence of seven ACR criteria (cutaneous lesions, photosensitivity, antinuclear and anti-double-stranded-DNA antibodies, pancytopenia, arthriti...

Jaccoud’s arthropathy in primary biliary cirrhosis.

Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic liver disease with fibrosis leading to cirrhosis [1–3] and liver failure [4,5]. PBC is often thought of as an organ-specific autoimmune disease, which mainly targets the liver; however, other tissue also can be a site for autoimmune involvement of PBC. Jaccoud’s arthropathy (JA) was a nonerosive deforming arthropathy initially...

Is there any Association Between Human Lymphotropic Virus Type I (HTLV-I) Infection and Systemic Lupus Erythematosus? An Original Research and Literature Review

Cigarette smoking and autoimmune disease: what can we learn from epidemiology?

Cigarette smoking has been causally linked to the development of multiple autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Graves' hyperthyroidism, and primary biliary cirrhosis, among others. We review the known biologic effects of cigarette smoke, in particular its actions on the immune system, and the epidemiologic evidence associating sm...